Some medical conditions may interact with capecitabine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Note: If a drug has been approved for one use, physicians may elect to use this same drug for other problems if they believe it may be helpful.How Carboplatin Is Given:
Important things to remember about the side effects of Carboplatin:
The following side effects are common (occurring in greater than 30%) for patients taking Carboplatin:
Cisplatin is used to treat various types of cancer. It is a chemotherapy drug that contains platinum. It is used alone or in combination with other medications to slow or stop cancer cell growth.How to use cisplatin intravenous
This medication is usually given by injection into a vein by a health care professional. The dosage is based on your medical condition, body size, and response to therapy. Courses of cisplatin treatment should not be given more often than once every 3 to 4 weeks. Consult your doctor or pharmacist for more details.
During treatment with this medication, it is important that you take in more fluids than usual and pass urine frequently to help avoid kidney side effects. Intravenous fluids should be given with this medication. Also, ask your doctor how much fluid you should drink and follow these instructions carefully.
If this medication comes into contact with your skin, wash your skin right away and completely with soap and water.Side Effects
See also Warnings.
Nausea, vomiting, loss of appetite, diarrhea, and loss of taste may occur. Nausea and vomiting can be quite severe and persistent. Drug therapy is used to prevent or relieve nausea and vomiting. Not eating before your treatment may help relieve vomiting. Changes in diet such as eating several small meals or limiting activity may help lessen some of these effects. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
Temporary hair loss may occur. Normal hair growth should return after treatment has ended.Precautions
Before using cisplatin, tell your doctor or pharmacist if you are allergic to it; or to carboplatin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Naivex is an antiviral drug designed to treat HIV-1 infection in adults and children 12 years of age and weighing 40 kg or more as part of combination antiretroviral therapy. The drug is recommended for use in patients who have not received therapy ("naive"), and in patients with HAART. In some cases, it can be used in patients with partial resistance to integrase inhibitors.
Manufacturer - Hetero Ltd, India. The active substance is Dolutegravir. Dolutegravir in 2013-2014 is approved in many countries of the world as one of the components of highly active antiretroviral therapy, such as the USA, Canada, Mexico, Brazil, the EU, Russia, Japan, Australia, South Africa.Dolutegravir user guide
Dolutegravir inhibits HIV integration by binding to the active region of integrase and blocking the chain transfer during the integration of retroviral deoxyribonucleic acid (DNA), which is necessary for the HIV replication cycle. In vitro, dolutegravir is slowly separated from the active site of the wild-type DNA integrase complex (half-life of 71 hours).
- Hypersensitivity reactions to dolutegravir (and auxiliary substances).
- Admission of anti-arrhythmic drug Dofetilide (English name Tikosyn)
- Age is less than 12 years and body weight is less than 40 kg
Dolutegravir is rapidly absorbed after ingestion. The average time to reach the maximum concentration is 2-3 hours. When you take 1 time per day, the pharmacokinetic steady state is reached approximately 5 days after the beginning of the oral administration. Food increases the degree and reduces the rate of absorption of dolutegravir. These changes are generally clinically insignificant, so Instgra can be taken regardless of food intake. However, patients infected with HIV-1 with a certain resistance to integrase inhibitors are advised to take Naivex with food.
Co-infection with hepatitis C does not matter for the pharmacokinetics of dolutegravir. Data on co-infection with hepatitis B are limited.